Spider-Man: Return of the Sinister Six is a 1992 action-adventure video game featuring the Marvel Comics characters Spider-Man and the Sinister Six. It was developed by Bits Studios and published by Acclaim Entertainment under the LJN banner for the Nintendo Entertainment System in 1992. Versions of the game were also released for the Master System and Game Gear by Acclaim's Flying Edge division. The game is loosely based on the story arc of the same name, which was published in The Amazing Spider-Man #334-339 in the early 1990s.